![]() ![]() ![]() Fetal swallowing of fluid aids in the development of the digestive system. Amniotic fluid is inhaled, helping to develop the respiratory system.Amniotic fluid has bacteriostatic properties that helps prevent ascending infection of the intra-amniotic environment. Amniotic fluid contains water, nutrients, hormones, and antibodies.After 20 weeks of pregnancy, the baby takes over fluid production and fluid is produced through a cycle of urination and exhalation of fluid. ![]() Amniotic fluid in the beginning of pregnancy consists of water delivered from the mother via the umbilical cord and through trans-membranous exchange.The sac provides a barrier from contaminants, pathogens and microorganisms that could ascend and cause intra-amniotic infection. The amniotic sac holds the baby in the uterus, protecting from damage and helping to regulate the baby’s temperature.Pathophysiology of the Intrauterine Environment The most common pregnancy complications related to PPROM are intra-amniotic infection (chorioamnionitis), pulmonary hypoplasia, and premature birth.Women have experienced PPROM in all trimesters of pregnancy.PPROM complicates 2% to 4% of all singleton and 7% to 20% of twin pregnancies.PPROM is responsible for 30-40 percent of preterm births, and impacts 150,000 women in the U.S.During pregnancy, if the amniotic sac or “water” breaks prior to 37 weeks, this is considered Preterm Premature Rupture of Membranes (PPROM) 1 ![]()
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